Management of a Patient with Metastatic Colorectal Cancer and Liver Metastases
Author
Source
Case Reports in Oncological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Liver metastases are commonly encountered in patients presenting with metastatic colorectal cancer (mCRC); resection is the treatment of choice.
A number of systemic treatment options are currently available for such patients, including the use of 5-fluorouracil-based chemotherapies and oxaliplatin (e.g., FOLFOX) in combination with biologic agents that target angiogenesis (e.g., bevacizumab).
For patients with progression following first-line treatment, current second-line options include a change in chemotherapy with bevacizumab (for patients who did or did not receive prior bevacizumab) or FOLFIRI in combination with aflibercept, a more recently approved antiangiogenesis therapy.
Neurotoxicity is a well-established adverse event of oxaliplatin-based therapy.
The current case details an mCRC patient with liver metastases who was treated with a capecitabine and oxaliplatin regimen (XELOX), and experienced two episodes of transient cortical blindness possibly related to oxaliplatin.
After disease progression, the patient was switched to a regimen of FOLFIRI and aflibercept and did well on this second-line regimen.
American Psychological Association (APA)
Saif, Muhammad Wasif. 2014. Management of a Patient with Metastatic Colorectal Cancer and Liver Metastases. Case Reports in Oncological Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-498262
Modern Language Association (MLA)
Saif, Muhammad Wasif. Management of a Patient with Metastatic Colorectal Cancer and Liver Metastases. Case Reports in Oncological Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-498262
American Medical Association (AMA)
Saif, Muhammad Wasif. Management of a Patient with Metastatic Colorectal Cancer and Liver Metastases. Case Reports in Oncological Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-498262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498262