![](/images/graphics-bg.png)
Induction of Specific Immunotherapy with Hymenoptera Venoms Using Ultrarush Regimen in Children : Safety and Tolerance
Joint Authors
Lauener, Roger
Stricker, Tamar
Stahlberger, Lisbeth
Bieli, Christian
Köhli-Wiesner, Alice
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background & Objective.
Ultrarush induction for specific venom immunotherapy has been shown to be reliable and efficacious in adults.
In this study its safety and tolerance in children was evaluated.
Methods.
Retrospective analysis of 102 ultrarush desensitizations carried out between 1997 and 2005 in 94 children, aged 4 to 15 years.
Diagnosis and selection for immunotherapy were according to recommendations of the European Academy of Allergy and Clinical Immunology.
Systemic adverse reactions (SARs) were described using the classification of H.
L.
Mueller.
Results.
All patients reached the cumulative dose of 111.1 μg hymenoptera venom within 210 minutes.
Six patients (6%) had allergic reactions grade I; 2 patients (2%) grade II and 5 patients (5%) grade III.
Three patients (3%) showed unclassified reactions.
SARs did not occur in the 15 patients aged 4 to 8 years and they were significantly more frequent in girls (29%) compared with boys (12%) (P=0.034, multivariant analysis) and in bee venom extract treated patients (20%) compared to those treated with wasp venom extract (8%) (OR 0.33, 95% Cl 0.07–1.25).
Conclusion.
Initiation of specific immunotherapy by ultrarush regimen is safe and well tolerated in children and should be considered for treating children with allergy to hymenoptera venom.
American Psychological Association (APA)
Köhli-Wiesner, Alice& Stahlberger, Lisbeth& Bieli, Christian& Stricker, Tamar& Lauener, Roger. 2011. Induction of Specific Immunotherapy with Hymenoptera Venoms Using Ultrarush Regimen in Children : Safety and Tolerance. Journal of Allergy،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-498347
Modern Language Association (MLA)
Köhli-Wiesner, Alice…[et al.]. Induction of Specific Immunotherapy with Hymenoptera Venoms Using Ultrarush Regimen in Children : Safety and Tolerance. Journal of Allergy No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-498347
American Medical Association (AMA)
Köhli-Wiesner, Alice& Stahlberger, Lisbeth& Bieli, Christian& Stricker, Tamar& Lauener, Roger. Induction of Specific Immunotherapy with Hymenoptera Venoms Using Ultrarush Regimen in Children : Safety and Tolerance. Journal of Allergy. 2011. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-498347
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498347