Atypical Creutzfeldt-Jakob Disease Evolution after Electroconvulsive Therapy for Catatonic Depression
Joint Authors
Flamarique, Itziar
Sánchez-Valle, Raquel
Blanch, Jordi
Fortea, Juan
Gelpi, Ellen
Udina, Marc
Grande, Iria
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-03
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We describe a case report of an 80-year-old woman who presented with symptomatology compatible with an episode of major depression with catatonia.
After psychiatric admission, electroconvulsive therapy (ECT) was applied, but symptoms progressed with cognitive impairment, bradykinesia, widespread stiffness, postural tremor, and gait disturbance.
After compatible magnetic resonance imaging (MRI), diffusion changes, and electroencephalogram (EEG) findings the case was reoriented to Creutzfeldt-Jakob disease (CJD).
The genetic study found a methionine/valine heterozygosity at codon 129 of the prion protein gene PrPSc.
On followup, a significant clinical recovery turned out.
For this reason, EEG and MRI were repeated and confirmed the findings.
The patient subsequently demonstrated progressive clinical deterioration and died 21 months later.
The diagnosis was verified postmortem by neuropathology.
The vCJD subtype MV2 is indeed characterized by early and prominent psychiatric symptoms and a prolonged disease duration however no frank clinical recovery has before been reported.
American Psychological Association (APA)
Grande, Iria& Fortea, Juan& Gelpi, Ellen& Flamarique, Itziar& Udina, Marc& Blanch, Jordi…[et al.]. 2011. Atypical Creutzfeldt-Jakob Disease Evolution after Electroconvulsive Therapy for Catatonic Depression. Case Reports in Psychiatry،Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-498377
Modern Language Association (MLA)
Grande, Iria…[et al.]. Atypical Creutzfeldt-Jakob Disease Evolution after Electroconvulsive Therapy for Catatonic Depression. Case Reports in Psychiatry No. 2011 (2011), pp.1-3.
https://search.emarefa.net/detail/BIM-498377
American Medical Association (AMA)
Grande, Iria& Fortea, Juan& Gelpi, Ellen& Flamarique, Itziar& Udina, Marc& Blanch, Jordi…[et al.]. Atypical Creutzfeldt-Jakob Disease Evolution after Electroconvulsive Therapy for Catatonic Depression. Case Reports in Psychiatry. 2011. Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-498377
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498377