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Neurospora crassa Light Signal Transduction Is Affected by ROS
Joint Authors
Deryabina, Yulia I.
Isakova, Elena P.
Gessler, Natalia N.
Belozerskaya, Tatiana A.
Source
Journal of Signal Transduction
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-20
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
In the ascomycete fungus Neurospora crassa blue-violet light controls the expression of genes responsible for differentiation of reproductive structures, synthesis of secondary metabolites, and the circadian oscillator activity.
A major photoreceptor in Neurospora cells is WCC, a heterodimeric complex formed by the PAS-domain-containing polypeptides WC-1 and WC-2, the products of genes white collar-1 and white collar-2.
The photosignal transduction is started by photochemical activity of an excited FAD molecule noncovalently bound by the LOV domain (a specialized variant of the PAS domain).
The presence of zinc fingers (the GATA-recognizing sequences) in both WC-1 and WC-2 proteins suggests that they might function as transcription factors.
However, a critical analysis of the phototransduction mechanism considers the existence of residual light responses upon absence of WCC or its homologs in fungi.
The data presented point at endogenous ROS generated by a photon stimulus as an alternative input to pass on light signals to downstream targets.
American Psychological Association (APA)
Belozerskaya, Tatiana A.& Gessler, Natalia N.& Isakova, Elena P.& Deryabina, Yulia I.. 2011. Neurospora crassa Light Signal Transduction Is Affected by ROS. Journal of Signal Transduction،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-498447
Modern Language Association (MLA)
Belozerskaya, Tatiana A.…[et al.]. Neurospora crassa Light Signal Transduction Is Affected by ROS. Journal of Signal Transduction No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-498447
American Medical Association (AMA)
Belozerskaya, Tatiana A.& Gessler, Natalia N.& Isakova, Elena P.& Deryabina, Yulia I.. Neurospora crassa Light Signal Transduction Is Affected by ROS. Journal of Signal Transduction. 2011. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-498447
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498447