The Involvement of Phospholipases A2 in Asthma and Chronic Obstructive Pulmonary Disease
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-13
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The increased morbidity, mortality, and ineffective treatment associated with the pathogenesis of chronic inflammatory diseases such as asthma and chronic obstructive pulmonary disease (COPD) have generated much research interest.
The key role is played by phospholipases from the A2 superfamily: enzymes which are involved in inflammation through participation in pro- and anti-inflammatory mediators production and have an impact on many immunocompetent cells.
The 30 members of the A2 superfamily are divided into 7 groups.
Their role in asthma and COPD has been studied in vitro and in vivo (animal models, cell cultures, and patients).
This paper contains complete and updated information about the involvement of particular enzymes in the etiology and course of asthma and COPD.
American Psychological Association (APA)
Pniewska, Ewa& Pawliczak, Rafal. 2013. The Involvement of Phospholipases A2 in Asthma and Chronic Obstructive Pulmonary Disease. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-498582
Modern Language Association (MLA)
Pniewska, Ewa& Pawliczak, Rafal. The Involvement of Phospholipases A2 in Asthma and Chronic Obstructive Pulmonary Disease. Mediators of Inflammation No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-498582
American Medical Association (AMA)
Pniewska, Ewa& Pawliczak, Rafal. The Involvement of Phospholipases A2 in Asthma and Chronic Obstructive Pulmonary Disease. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-498582
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498582