Finding a Balance : How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription
Joint Authors
Custer, Laura M.
Wells, Michael B.
Csankovszki, Györgyi
Source
Genetics Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-19
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Dosage compensation balances gene expression levels between the sex chromosomes and autosomes and sex-chromosome-linked gene expression levels between the sexes.
Different dosage compensation strategies evolved in different lineages, but all involve changes in chromatin.
This paper discusses our current understanding of how modifications of the histone H4 tail, particularly changes in levels of H4 lysine 16 acetylation and H4 lysine 20 methylation, can be used in different contexts to either modulate gene expression levels twofold or to completely inhibit transcription.
American Psychological Association (APA)
Wells, Michael B.& Csankovszki, Györgyi& Custer, Laura M.. 2011. Finding a Balance : How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription. Genetics Research International،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-498733
Modern Language Association (MLA)
Wells, Michael B.…[et al.]. Finding a Balance : How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription. Genetics Research International No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-498733
American Medical Association (AMA)
Wells, Michael B.& Csankovszki, Györgyi& Custer, Laura M.. Finding a Balance : How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription. Genetics Research International. 2011. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-498733
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498733
