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Antibiofilm Activity of Manuka Honey in Combination with Antibiotics
Joint Authors
Campeau, Michelle E. M.
Patel, Robin
Source
International Journal of Bacteriology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We assessed the in vitro activity of Manuka honey against biofilm bacteria in combination with antibiotics and visualized the effect of Manuka honey on bacterial biofilms using scanning electron microscopy.
The fractional biofilm eradication concentration (∑FBEC ) index for vancomycin plus Manuka honey against S.
aureus IDRL-4284 biofilms was 0.34, indicating a synergistic interaction.
The ∑FBEC index for gentamicin plus Manuka honey against P.
aeruginosa PAO1 biofilms was 0.78–0.82, indicating an additive interaction.
Scanning electron microscopy of S.
aureus IDRL-4284 and P.
aeruginosa PAO1 biofilms exposed to Manuka honey and artificial honey containing the same sugar composition as Manuka honey showed that the former had more pronounced effects than the latter on both S.
aureus and P.
aeruginosa biofilms.
Visualized effects included distorted cell morphologies for both bacteria and a decrease in P.
aeruginosa extracellular matrix.
In conclusion, Manuka honey has a synergistic interaction with vancomycin against S.
aureus biofilms and an additive interaction with gentamicin against P.
aeruginosa biofilms.
American Psychological Association (APA)
Campeau, Michelle E. M.& Patel, Robin. 2014. Antibiofilm Activity of Manuka Honey in Combination with Antibiotics. International Journal of Bacteriology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-498755
Modern Language Association (MLA)
Campeau, Michelle E. M.& Patel, Robin. Antibiofilm Activity of Manuka Honey in Combination with Antibiotics. International Journal of Bacteriology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-498755
American Medical Association (AMA)
Campeau, Michelle E. M.& Patel, Robin. Antibiofilm Activity of Manuka Honey in Combination with Antibiotics. International Journal of Bacteriology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-498755
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498755