Correlation between Group B Streptococcal Genotypes, Their Antimicrobial Resistance Profiles, and Virulence Genes among Pregnant Women in Lebanon
Joint Authors
Sabra, Ahmad
Khairallah, Marie-Therese
Matar, Ghassan M.
Hannoun, Antoine
Araj, George F.
Yunis, Khalid A.
Shehab, Marwa
Abi-Rached, Roland
Bazi, Tony
Source
International Journal of Microbiology
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
The antimicrobial susceptibility profiles of 76 Streptococcus agalactiae (Group B Streptococci [GBS]) isolates from vaginal specimens of pregnant women near term were correlated to their genotypes generated by Random Amplified Polymorphic DNA analysis and their virulence factors encoding genes cylE, lmb, scpB, rib, and bca by PCR.
Based on the distribution of the susceptibility patterns, six profiles were generated.
RAPD analysis detected 7 clusters of genotypes.
The cylE gene was present in 99% of the isolates, the lmb in 96%, scpB in 94.7%, rib in 33%, and bca in 56.5% of isolates.
The isolates demonstrated a significant correlation between antimicrobial resistance and genotype clusters denoting the distribution of particular clones with different antimicrobial resistance profiles, entailing the practice of caution in therapeutic options.
All virulence factors encoding genes were detected in all seven genotypic clusters with rib and bca not coexisting in the same genome.
American Psychological Association (APA)
Hannoun, Antoine& Shehab, Marwa& Khairallah, Marie-Therese& Sabra, Ahmad& Abi-Rached, Roland& Bazi, Tony…[et al.]. 2010. Correlation between Group B Streptococcal Genotypes, Their Antimicrobial Resistance Profiles, and Virulence Genes among Pregnant Women in Lebanon. International Journal of Microbiology،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-498868
Modern Language Association (MLA)
Hannoun, Antoine…[et al.]. Correlation between Group B Streptococcal Genotypes, Their Antimicrobial Resistance Profiles, and Virulence Genes among Pregnant Women in Lebanon. International Journal of Microbiology No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-498868
American Medical Association (AMA)
Hannoun, Antoine& Shehab, Marwa& Khairallah, Marie-Therese& Sabra, Ahmad& Abi-Rached, Roland& Bazi, Tony…[et al.]. Correlation between Group B Streptococcal Genotypes, Their Antimicrobial Resistance Profiles, and Virulence Genes among Pregnant Women in Lebanon. International Journal of Microbiology. 2010. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-498868
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498868
