Antidepressant Drugs for Chronic Urological Pelvic Pain : An Evidence-Based Review
Joint Authors
Skapinakis, Petros
Papandreou, Christos
Sofikitis, Nikolaos
Mavreas, Venetsanos
Giannakis, Dimitrios
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-14
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The use of antidepressant drugs for the management of chronic pelvic pain has been supported in the past.
This study aimed to evaluate the available evidence for the efficacy and acceptability of antidepressant drugs in the management of urological chronic pelvic pain.
Studies were selected through a comprehensive literature search.
We included all types of study designs due to the limited evidence.
Studies were classified into levels of evidence according to their design.
Ten studies were included with a total of 360 patients.
Amitriptyline, sertraline, duloxetine, nortriptyline, and citalopram are the antidepressants that have been reported in the literature.
Only four randomized controlled trials (RCTs) were identified (two for amitriptyline and two for sertraline) with mixed results.
We conclude that the use of antidepressants for the management of chronic urological pelvic pain is not adequately supported by methodologically sound RCTs.
From the existing studies amitriptyline may be effective in interstitial cystitis but publication bias should be considered as an alternative explanation.
All drugs were generally well tolerated with no serious events reported.
American Psychological Association (APA)
Papandreou, Christos& Skapinakis, Petros& Giannakis, Dimitrios& Sofikitis, Nikolaos& Mavreas, Venetsanos. 2010. Antidepressant Drugs for Chronic Urological Pelvic Pain : An Evidence-Based Review. Advances in Urology،Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-498901
Modern Language Association (MLA)
Papandreou, Christos…[et al.]. Antidepressant Drugs for Chronic Urological Pelvic Pain : An Evidence-Based Review. Advances in Urology No. 2009 (2009), pp.1-9.
https://search.emarefa.net/detail/BIM-498901
American Medical Association (AMA)
Papandreou, Christos& Skapinakis, Petros& Giannakis, Dimitrios& Sofikitis, Nikolaos& Mavreas, Venetsanos. Antidepressant Drugs for Chronic Urological Pelvic Pain : An Evidence-Based Review. Advances in Urology. 2010. Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-498901
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498901