Intracranial Blood Flow Velocity in Patients with β-Thalassemia Intermedia Using Transcranial Doppler Sonography : A Case-Control Study
Joint Authors
Yaghoubi, Ehsan
Emami, Sajad
Karimi, Mahran
Petramfar, Peyman
Ashjazadeh, Nahid
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Patients with β-thalassemia intermedia have a higher incidence of thromboembolic events compared to the general population.
Previous studies have shown that patients with sickle cell disease, who are also prone to ischemic events, have higher intracranial arterial blood flow velocities measured by transcranial Doppler sonography (TCD).
The aim of this study is to evaluate intracranial arterial flow velocities in patients with β-thalassemia intermedia and compare the results with those found in healthy subjects.
Methods.
Sixty-four patients with β-thalassemia intermedia and 30 healthy subjects underwent transcranial Doppler sonography.
Results.
Significantly higher flow velocities were found in intracranial arteries of patients compared to controls (P=0.001).
Previously splenectomized patients with thrombocytosis showed higher flow velocities than nonsplenectomized patients without thrombosis.
Conclusion.
The increased flow velocities in patients with β-thalassemia intermedia may point to a higher risk of ischemic events.
Preventive measures such as blood transfusion or antiplatelet treatment may be beneficial in these patients.
American Psychological Association (APA)
Ashjazadeh, Nahid& Emami, Sajad& Petramfar, Peyman& Yaghoubi, Ehsan& Karimi, Mahran. 2011. Intracranial Blood Flow Velocity in Patients with β-Thalassemia Intermedia Using Transcranial Doppler Sonography : A Case-Control Study. Anemia،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-499014
Modern Language Association (MLA)
Ashjazadeh, Nahid…[et al.]. Intracranial Blood Flow Velocity in Patients with β-Thalassemia Intermedia Using Transcranial Doppler Sonography : A Case-Control Study. Anemia No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-499014
American Medical Association (AMA)
Ashjazadeh, Nahid& Emami, Sajad& Petramfar, Peyman& Yaghoubi, Ehsan& Karimi, Mahran. Intracranial Blood Flow Velocity in Patients with β-Thalassemia Intermedia Using Transcranial Doppler Sonography : A Case-Control Study. Anemia. 2011. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-499014
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499014