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Effect of the Zataria multiflora on Systemic Inflammation of Experimental Animals Model of COPD
Joint Authors
Gholami Mhtaj, Lilla
Boskabady, Mohammad Hossein
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The effects of Zataria multiflora (Z.
multiflora) on systemic inflammation in guinea pigs model of COPD were examined.
Control animals, COPD (induced by exposing animals to cigarette smoke), COPD + drinking water containing three concentrations of the extract of Z.
multiflora, and COPD + dexamethasone were studied (n=6 for each group).
Serum levels of IL-8 and malondialdehyde (MDA), total blood WBC (P<0.01 for all cases), and eosinophil counts (P<0.05) were higher and weight changes (P<0.05) were lower in the COPD group compared to controls.
IL-8 level (P<0.001) and weight changes (P<0.01 to P<0.001) in all treated groups with Z.
multiflora and total WBC number and MDA level in treated groups with two higher concentrations of the extract and lymphocytes percentage (P<0.05) in the highest concentration of Z.
multiflora and dexamethasone (P<0.05 to P<0.001) were significantly improved compared to the COPD group.
Results showed a preventive effect of hydroethanolic extract from Z.
multiflora on all measured parameters in animals model of COPD which was comparable or even higher (in the highest concentration) compared to the effect of dexamethasone at the concentration used.
American Psychological Association (APA)
Boskabady, Mohammad Hossein& Gholami Mhtaj, Lilla. 2014. Effect of the Zataria multiflora on Systemic Inflammation of Experimental Animals Model of COPD. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-499194
Modern Language Association (MLA)
Boskabady, Mohammad Hossein& Gholami Mhtaj, Lilla. Effect of the Zataria multiflora on Systemic Inflammation of Experimental Animals Model of COPD. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-499194
American Medical Association (AMA)
Boskabady, Mohammad Hossein& Gholami Mhtaj, Lilla. Effect of the Zataria multiflora on Systemic Inflammation of Experimental Animals Model of COPD. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-499194
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499194