The Current Knowledge of the Role of PPAR in Hepatic Ischemia-Reperfusion Injury
Joint Authors
Jiménez-Castro, M. B.
Elias-Miró, M.
Casillas-Ramírez, A.
Peralta, C.
Mendes-Braz, M.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-16
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Strategies to improve the viability of steatotic livers could reduce the risk of dysfunction after surgery and increase the number of organs suitable for transplantation.
Peroxisome proliferator-activated receptors (PPARs) are major regulators of lipid metabolism and inflammation.
In this paper, we review the PPAR signaling pathways and present some of their lesser-known functions in liver regeneration.
Potential therapies based on PPAR regulation will be discussed.
The data suggest that further investigations are required to elucidate whether PPAR could be a potential therapeutic target in liver surgery and to determine the most effective therapies that selectively regulate PPAR with minor side effects.
American Psychological Association (APA)
Elias-Miró, M.& Jiménez-Castro, M. B.& Mendes-Braz, M.& Casillas-Ramírez, A.& Peralta, C.. 2012. The Current Knowledge of the Role of PPAR in Hepatic Ischemia-Reperfusion Injury. PPAR Research،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-499204
Modern Language Association (MLA)
Elias-Miró, M.…[et al.]. The Current Knowledge of the Role of PPAR in Hepatic Ischemia-Reperfusion Injury. PPAR Research No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-499204
American Medical Association (AMA)
Elias-Miró, M.& Jiménez-Castro, M. B.& Mendes-Braz, M.& Casillas-Ramírez, A.& Peralta, C.. The Current Knowledge of the Role of PPAR in Hepatic Ischemia-Reperfusion Injury. PPAR Research. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-499204
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499204