Gut Microbiota in HIV Infection : Implication for Disease Progression and Management
Joint Authors
Avershina, Ekaterina
Rudi, Knut
Wilson, Robert
Nwosu, Felix Chinweije
Source
Gastroenterology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Survival rates among HIV patients have significantly improved since the introduction of antiretroviral therapy (ART) in HIV management.
However, persistent disease progression and clinical complications in virally suppressed individuals point to additional contributing factors other than HIV replication; microbial translocation is one such factor.
The role of underlying commensal microbes and microbial products that traverse the intestinal lumen into systemic circulation in the absence of overt bacteraemia is under current investigation.
This review focuses on current knowledge of the complex microbial communities and microbial markers involved in the disruption of mucosal immune T-cells in the promotion of inflammatory processes in HIV infections.
Unanswered questions and aims for future studies are addressed.
We provide perspective for discussing potential future therapeutic strategies focused on modulating the gut microbiota to abate HIV disease progression.
American Psychological Association (APA)
Nwosu, Felix Chinweije& Avershina, Ekaterina& Wilson, Robert& Rudi, Knut. 2014. Gut Microbiota in HIV Infection : Implication for Disease Progression and Management. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-499278
Modern Language Association (MLA)
Nwosu, Felix Chinweije…[et al.]. Gut Microbiota in HIV Infection : Implication for Disease Progression and Management. Gastroenterology Research and Practice No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-499278
American Medical Association (AMA)
Nwosu, Felix Chinweije& Avershina, Ekaterina& Wilson, Robert& Rudi, Knut. Gut Microbiota in HIV Infection : Implication for Disease Progression and Management. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-499278
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499278