Skin and Soft Tissue Infections in Patients with Solid Tumours
Joint Authors
Samonis, George
Koutsounaki, Eirini
Mavrogeni, Eleni
Dimopoulou, Dimitra
Kofteridis, Diamantis P.
Georgoulias, Vassilios A.
Kalbakis, Kostas
Maraki, Sofia
Economidou, Foteini N.
Valachis, Antonios
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Background.
Skin and soft tissue infections (SSTIs) in cancer patients represent a diagnostic challenge, as etiologic diagnosis is often missing, and clinical assessment of severity is difficult.
Few studies have described (SSTIs) in patients with solid tumours (STs).
Patients and Methods.
Records of patients with ST and SSTI, cared for at the University Hospital of Heraklion, from 2002 to 2006 were retrospectively studied.
Results.
A total of 81 episodes of SSTIs, occurring in 71 patients with ST, have been evaluated.
Their median age was 65 years (34–82).
The most common underlying malignancy was breast cancer in 17 patients (24%).
Most episodes (89%) occurred in nonneutropenics.
Cellulitis/erysipelas was the most common clinical presentation (56; 69%).
Bacterial cultures were possible in 29 (36%) patients.
All patients received antimicrobial therapy, while in 17 episodes (21%) an incision and drainage was required.
Treatment failure occurred in 20 episodes (25%).
Five patients (7%) died due to sepsis.
None was neutropenic.
Severe sepsis on admission (P=0.002) and prior blood transfusion (P=0.043) were independent predictors of treatment failure.
Conclusion.
SSTIs can be life threatening among patients with ST.
Early diagnosis and appropriate treatment are of the utmost importance, since sepsis was proven a significant factor of unfavourable outcome.
American Psychological Association (APA)
Kofteridis, Diamantis P.& Valachis, Antonios& Koutsounaki, Eirini& Maraki, Sofia& Mavrogeni, Eleni& Economidou, Foteini N.…[et al.]. 2012. Skin and Soft Tissue Infections in Patients with Solid Tumours. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-499387
Modern Language Association (MLA)
Kofteridis, Diamantis P.…[et al.]. Skin and Soft Tissue Infections in Patients with Solid Tumours. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-499387
American Medical Association (AMA)
Kofteridis, Diamantis P.& Valachis, Antonios& Koutsounaki, Eirini& Maraki, Sofia& Mavrogeni, Eleni& Economidou, Foteini N.…[et al.]. Skin and Soft Tissue Infections in Patients with Solid Tumours. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-499387
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499387