Cytokines and Oxidative Stress Status Following a Handball Game in Elite Male Players
Joint Authors
Marin, Douglas Popp
Hatanaka, Elaine
Bolin, Anaysa Paola
Otton, Rosemari
Macedo dos Santos, Rita de Cassia
Guerra, Beatriz Alves
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Background.
Handball is considered an intermittent sport that places an important stress on a player's aerobic and anaerobic metabolism.
However, the oxidative stress responses following a handball game remain unknown.
We investigated the responses of plasma and erythrocyte antioxidant system and oxidative stress biomarkers following a single handball game.
Methods.
Fourteen male elite Brazilian handball athletes were recruited in the present study.
Blood samples were taken before, immediately, and 24 hours after the game.
Results.
After the game and during 24 hours of recovery, the concentration of all oxidative stress indices changed significantly in a way indicating increased oxidative stress in the blood (thiol groups and reduced glutathione decreased, whereas TBARS and plasma antioxidant capacity was increased) as well as in erythrocyte (increased levels of TBARS and protein carbonyls).
Erythrocyte antioxidant enzyme activities were also significantly changed by handball.
Muscle damage indices (creatine kinase and lactate dehydrogenase) increased significantly after exercise.
In addition, IL-6 increased after the game, whereas TNF-α decreased during recovery.
Conclusion.
This study demonstrates that a single handball game in elite athletes induces a marked state of oxidative stress evidenced by the oxidative modification in plasma and erythrocyte macromolecules, as well as by changes in the enzymatic and nonenzymatic antioxidant system.
American Psychological Association (APA)
Marin, Douglas Popp& Macedo dos Santos, Rita de Cassia& Bolin, Anaysa Paola& Guerra, Beatriz Alves& Hatanaka, Elaine& Otton, Rosemari. 2011. Cytokines and Oxidative Stress Status Following a Handball Game in Elite Male Players. Oxidative Medicine and Cellular Longevity،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-499428
Modern Language Association (MLA)
Marin, Douglas Popp…[et al.]. Cytokines and Oxidative Stress Status Following a Handball Game in Elite Male Players. Oxidative Medicine and Cellular Longevity No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-499428
American Medical Association (AMA)
Marin, Douglas Popp& Macedo dos Santos, Rita de Cassia& Bolin, Anaysa Paola& Guerra, Beatriz Alves& Hatanaka, Elaine& Otton, Rosemari. Cytokines and Oxidative Stress Status Following a Handball Game in Elite Male Players. Oxidative Medicine and Cellular Longevity. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-499428
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499428