Maternal Moderate Physical Training during Pregnancy Attenuates the Effects of a Low-Protein Diet on the Impaired Secretion of Insulin in Rats : Potential Role for Compensation of Insulin Resistance and Preventing Gestational Diabetes Mellitus
Joint Authors
Leandro, Carol Góis
Falcão-Tebas, Filippe
Curi, Rui
Manhães-de-Castro, Raul
Carpinelli, Angelo Rafael
Fidalgo, Marco
Hirabara, Sandro Massao
Vasconcelos, Diogo
Bento-Santos, Adriano
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The effects of pregestational and gestational low-to-moderate physical training on insulin secretion in undernourished mothers were evaluated.
Virgin female Wistar rats were divided into four groups as follows: control (C, n=5); trained (T, n=5); low-protein diet (LP, n=5); trained with a low-protein diet (T + LP, n=5).
Trained rats ran on a treadmill over a period of 4 weeks before mate (5 days week−1 and 60 min day−1, at 65% of VO2max).
At pregnancy, the intensity and duration of the exercise were reduced.
Low-protein groups were provided with an 8% casein diet, and controls were provided with a 17% casein diet.
At third day after delivery, mothers and pups were killed and islets were isolated by collagenase digestion of pancreas and incubated for a further 1 h with medium containing 5.6 or 16.7 mM glucose.
T mothers showed increased insulin secretion by isolated islets incubated with 16.7 mM glucose, whereas LP group showed reduced secretion of insulin by isolated islets when compared with both C and LP + T groups.
Physical training before and during pregnancy attenuated the effects of a low-protein diet on the secretion of insulin, suggesting a potential role for compensation of insulin resistance and preventing gestational diabetes mellitus.
American Psychological Association (APA)
Leandro, Carol Góis& Fidalgo, Marco& Bento-Santos, Adriano& Falcão-Tebas, Filippe& Vasconcelos, Diogo& Manhães-de-Castro, Raul…[et al.]. 2012. Maternal Moderate Physical Training during Pregnancy Attenuates the Effects of a Low-Protein Diet on the Impaired Secretion of Insulin in Rats : Potential Role for Compensation of Insulin Resistance and Preventing Gestational Diabetes Mellitus. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-499470
Modern Language Association (MLA)
Leandro, Carol Góis…[et al.]. Maternal Moderate Physical Training during Pregnancy Attenuates the Effects of a Low-Protein Diet on the Impaired Secretion of Insulin in Rats : Potential Role for Compensation of Insulin Resistance and Preventing Gestational Diabetes Mellitus. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-499470
American Medical Association (AMA)
Leandro, Carol Góis& Fidalgo, Marco& Bento-Santos, Adriano& Falcão-Tebas, Filippe& Vasconcelos, Diogo& Manhães-de-Castro, Raul…[et al.]. Maternal Moderate Physical Training during Pregnancy Attenuates the Effects of a Low-Protein Diet on the Impaired Secretion of Insulin in Rats : Potential Role for Compensation of Insulin Resistance and Preventing Gestational Diabetes Mellitus. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-499470
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499470