The Prevalence of Vitamin D Deficiency Is Similar between Thyroid Nodule and Thyroid Cancer Patients

Abstract EN

Introduction.

There are reported associations between vitamin D deficiency and breast, prostate, and colon cancer, but the relationship in thyroid cancer has not been evaluated.

Methods.

We evaluated serum calcium, creatinine, albumin, and 25-hydroxy vitamin D (25-OH-D) in 42 thyroid nodule, 45 thyroid cancer in remission, and 24 active thyroid cancer patients.

Results.

25-OH-D was not different between groups.

The percent with 25-OH-D levels <75 nmol/L was not significantly different between groups and was not affected by season of measurement, age, or cancer stage.

Multivariate regression showed a BMI of ≥30 kg/m2 to be the only significant predictor of vitamin D deficiency.

Conclusions.

Rates of vitamin D deficiency are similar in thyroid nodules and thyroid cancer, although higher than the general population.

This is different than previous studies for other cancers, which show higher rates of vitamin D deficiency.

BMI was the only predictor of vitamin D deficiency.