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Screening for Microalbuminuria in HIV-Positive Children in Enugu
Joint Authors
Tagbo, Oguonu
Bertilla Uzoma, Ezeonwu
Anthony Nnaemeka, Ikefuna
Henrietta Uchenna, Okafor
Source
International Journal of Nephrology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Human immunodeficiency virus associated nephropathy (HIVAN) is a rapidly progressive chronic renal parenchymal disease that occurs in HIV-infected individuals and manifests commonly as proteinuria, which is preceded by microalbuminuria (MA).
This clinical entity is defined as a spot urine albumin of 20–200 mg/L.
Objectives.
To determine the prevalence of microalbuminuria in HIV positive children in UNTH, Enugu and compare it with that of HIV-negative children.
Methods.
A total of 154 HIV positive children aged 18 months to 14 years and 154 HIV-negative children of corresponding attributes were screened for microalbuminuria, using Micral test II strip which has a sensitivity of 90–99%.
Results.
No child among the groups (HIV positive and negative) had microalbuminuria.
Majority (96.0%) of HIV-positive children had nonadvanced HIV disease at the time of the study (P=0.00).
About 77.3% were using HAART (P<0.0001), the mean CD4 cell count of the subjects was 709.2±443.9 cells/mm3; while 78.0% had nonsevere immunosuppression (P=0.00).
Furthermore, HIV-positive children with severe immunosuppression were younger and had shorter duration of treatment.
Conclusion.
Microalbuminuria may not be very common in Nigerian children irrespective of their HIV status.
American Psychological Association (APA)
Bertilla Uzoma, Ezeonwu& Henrietta Uchenna, Okafor& Anthony Nnaemeka, Ikefuna& Tagbo, Oguonu. 2012. Screening for Microalbuminuria in HIV-Positive Children in Enugu. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-499498
Modern Language Association (MLA)
Bertilla Uzoma, Ezeonwu…[et al.]. Screening for Microalbuminuria in HIV-Positive Children in Enugu. International Journal of Nephrology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-499498
American Medical Association (AMA)
Bertilla Uzoma, Ezeonwu& Henrietta Uchenna, Okafor& Anthony Nnaemeka, Ikefuna& Tagbo, Oguonu. Screening for Microalbuminuria in HIV-Positive Children in Enugu. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-499498
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499498