A Case of an Unusually Aggressive Cutaneous Anaplastic Large T-Cell Lymphoma in an HIV Patient Treated with CHOP
Joint Authors
Hurtado-Cordovi, Jorge M.
Gotlieb, Vladimir
Multz, Alan S.
Hanna, Louay
Pigal, Anastasia
Source
Case Reports in Oncological Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Anaplastic large cell lymphoma (ALCL) is the second most common malignancy of T-cell phenotype.
This case report describes an unusual rapidly progressing cutaneous anaplastic large T-cell lymphoma in an HIV patient.
Our patient is a twenty-year-old African American male with perinatally acquired HIV who presented with a 2×2 centimeter necrotic lesion in the right 1st toe; however, 2-3 weeks later multiple smaller lesions appeared on the anterior aspect of the right foot, ankle, and thigh.
Biopsy showed cells strongly positive for CD3 and CD30 and negative for CD56 and the ALK gene product.
CT of the chest, abdomen, and pelvis was negative for extracutaneous involvement favoring cutaneous ALCL.
Patient was treated with 6 cycles of CHOP (cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisone) chemotherapy and went into complete remission.
Due to the aggressive course that this malignancy follows in HIV patients we suggest prompt treatment with systemic therapy.
American Psychological Association (APA)
Hurtado-Cordovi, Jorge M.& Hanna, Louay& Gotlieb, Vladimir& Multz, Alan S.& Pigal, Anastasia. 2011. A Case of an Unusually Aggressive Cutaneous Anaplastic Large T-Cell Lymphoma in an HIV Patient Treated with CHOP. Case Reports in Oncological Medicine،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-499504
Modern Language Association (MLA)
Hurtado-Cordovi, Jorge M.…[et al.]. A Case of an Unusually Aggressive Cutaneous Anaplastic Large T-Cell Lymphoma in an HIV Patient Treated with CHOP. Case Reports in Oncological Medicine No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-499504
American Medical Association (AMA)
Hurtado-Cordovi, Jorge M.& Hanna, Louay& Gotlieb, Vladimir& Multz, Alan S.& Pigal, Anastasia. A Case of an Unusually Aggressive Cutaneous Anaplastic Large T-Cell Lymphoma in an HIV Patient Treated with CHOP. Case Reports in Oncological Medicine. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-499504
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499504