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The Pharmacopsychometric Triangle to Illustrate the Effectiveness of T-PEMF Concomitant with Antidepressants in Treatment Resistant Patients : A Double-Blind, Randomised, Sham-Controlled Trial Revisited with Focus on the Patient-Reported Outcomes
Joint Authors
Martiny, K.
Gefke, M.
Lauritzen, L.
Lunde, Marianne
Bech, Per
Source
Depression Research and Treatment
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Our T-PEMF trial has been revisited with focus on the pharmacopsychometric triangle in which effect size is used when comparing wanted versus unwanted clinical effects and quality of life as outcomes.
In this analysis, we have especially focused on the self-reported HAM-D6.
Methods.
The antidepressive medication which the patients were resistant to was kept unchanged during the five weeks of active versus sham T-PEMF.
Results.
In total 21, patients received active T-PEMF, and 19 patients received sham T-PEMF.
The effect size was 1.02 and 0.90, respectively, on HAM-D6 and HAM-D6-S.
Concerning side effects, the active T-PEMF reduced the baseline score on concentration problems with an effect size of 0.44 while inducing more autonomic symptoms than sham T-PEMF with an effect size of −0.41.
The advantage of active over sham T-PEMF obtained an effect size of 0.48.
Conclusion.
Active T-PEMF was found superior to sham T-PEMF within the pharmacopsychometric triangle with a clinically significant effect size level above 0.40.
American Psychological Association (APA)
Bech, Per& Gefke, M.& Lunde, Marianne& Lauritzen, L.& Martiny, K.. 2011. The Pharmacopsychometric Triangle to Illustrate the Effectiveness of T-PEMF Concomitant with Antidepressants in Treatment Resistant Patients : A Double-Blind, Randomised, Sham-Controlled Trial Revisited with Focus on the Patient-Reported Outcomes. Depression Research and Treatment،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-499552
Modern Language Association (MLA)
Bech, Per…[et al.]. The Pharmacopsychometric Triangle to Illustrate the Effectiveness of T-PEMF Concomitant with Antidepressants in Treatment Resistant Patients : A Double-Blind, Randomised, Sham-Controlled Trial Revisited with Focus on the Patient-Reported Outcomes. Depression Research and Treatment No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-499552
American Medical Association (AMA)
Bech, Per& Gefke, M.& Lunde, Marianne& Lauritzen, L.& Martiny, K.. The Pharmacopsychometric Triangle to Illustrate the Effectiveness of T-PEMF Concomitant with Antidepressants in Treatment Resistant Patients : A Double-Blind, Randomised, Sham-Controlled Trial Revisited with Focus on the Patient-Reported Outcomes. Depression Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-499552
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499552