ALS and Frontotemporal Dysfunction : A Review
Joint Authors
Rudnicki, Stacy A.
Achi, Eugene Y.
Source
Neurology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Though once believed to be a disease that was limited to the motor system, it is now apparent that amyotrophic lateral sclerosis (ALS) may be associated with cognitive changes in some patients.
Changes are consistent with frontotemporal dysfunction, and may range from mild abnormalities only recognized with formal neuropsychological testing, to profound frontotemporal dementia (FTD).
Executive function, behavior, and language are the most likely areas to be involved.
Screening helpful in detecting abnormalities includes verbal or categorical fluency, behavioral inventories filled out by the caregiver, and evaluation for the presence of depression and pseudobulbar affect.
Patients with cognitive dysfunction have shortened survival and may be less compliant with recommendations regarding use of feeding tubes and noninvasive ventilation.
Evolving knowledge of genetic and pathological links between ALS and FTD has allowed us to better understand the overlapping spectrum of ALS and FTD.
American Psychological Association (APA)
Achi, Eugene Y.& Rudnicki, Stacy A.. 2012. ALS and Frontotemporal Dysfunction : A Review. Neurology Research International،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-499553
Modern Language Association (MLA)
Achi, Eugene Y.& Rudnicki, Stacy A.. ALS and Frontotemporal Dysfunction : A Review. Neurology Research International No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-499553
American Medical Association (AMA)
Achi, Eugene Y.& Rudnicki, Stacy A.. ALS and Frontotemporal Dysfunction : A Review. Neurology Research International. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-499553
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499553