Cyanoacrylate Injection Compared with Band Ligation for Acute Gastric Variceal Hemorrhage : A Meta-Analysis of Randomized Controlled Trials and Observational Studies
Joint Authors
Huai, Jiaping
Chen, Yanping
Ye, Xiaohua
Source
Gastroenterology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-24
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Background.
Cyanoacrylate injection (GVO) and band ligation (GVL) are effective treatments for gastric variceal hemorrhage.
However, data on the optimal treatment are still controversial.
Methods.
For our overall analysis, relevant studies were identified from several databases.
For each outcome, data were pooled using a fixed-effect or random-effects model according to the result of a heterogeneity test.
Results.
Seven studies were included.
Compared with GVL, GVO was associated with increased likelihood of hemostasis of active bleeding (odds ratio [OR] = 2.32; 95% confidence interval [CI] = 1.19–4.51) and a longer gastric variceal rebleeding-free period (hazard ratio = 0.37; 95% CI = 0.24–0.56).
No significant differences were observed between GVL and GVO for mortality (hazard ratio = 0.66; 95% CI = 0.43–1.02), likelihood of variceal obliteration (OR = 0.89; 95% CI = 0.52–1.54), number of treatment sessions required for complete variceal eradication (weighted mean difference = −0.45; 95% CI = −1.14–0.23), or complications (OR = 1.02; 95% CI = 0.48–2.19).
Conclusion.
GVO may be superior to GVL for achieving hemostasis and preventing recurrence of gastric variceal rebleeding but has no advantage over GVL for mortality and complications.
Additional studies are warranted to enable definitive conclusions.
American Psychological Association (APA)
Ye, Xiaohua& Huai, Jiaping& Chen, Yanping. 2014. Cyanoacrylate Injection Compared with Band Ligation for Acute Gastric Variceal Hemorrhage : A Meta-Analysis of Randomized Controlled Trials and Observational Studies. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-499582
Modern Language Association (MLA)
Ye, Xiaohua…[et al.]. Cyanoacrylate Injection Compared with Band Ligation for Acute Gastric Variceal Hemorrhage : A Meta-Analysis of Randomized Controlled Trials and Observational Studies. Gastroenterology Research and Practice No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-499582
American Medical Association (AMA)
Ye, Xiaohua& Huai, Jiaping& Chen, Yanping. Cyanoacrylate Injection Compared with Band Ligation for Acute Gastric Variceal Hemorrhage : A Meta-Analysis of Randomized Controlled Trials and Observational Studies. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-499582
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499582