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Component-Resolved Diagnosis in Pediatrics
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Component resolved diagnosis is a new concept in the investigation of pediatric allergic disease.
The aim of the present paper is to review the available data on component resolved diagnosis with respect to implications for investigation of children with allergic disease.
In most conditions head-to-head comparisons of component resolved diagnosis with traditional IgE testing have not been performed.
Rather than alternatives the molecular methods should be seen as adjuncts to the cheaper traditional specific IgE tests.
It may be appropriate to determine IgE antibodies to components as part of the diagnostic work-up in selected cases of peanut and birch pollen allergy and in hymenoptera allergy.
However, cost benefit analyses of component resolved diagnosis compared with traditional work-up of allergy are needed.
Prospectively planned protocols for assessment of the extent to which component resolved diagnosis may be able to improve the selection of children to immunotherapy and, thus, the efficacy of immunotherapy, are needed.
Finally, studies of component resolved diagnosis with microarray technology in screening panels with hundreds of components should be undertaken before it can be determined to which extent such panel screening, if at all, may be helpful in children.
American Psychological Association (APA)
Wolthers, Ole D.. 2012. Component-Resolved Diagnosis in Pediatrics. ISRN Pediatrics،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-499612
Modern Language Association (MLA)
Wolthers, Ole D.. Component-Resolved Diagnosis in Pediatrics. ISRN Pediatrics No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-499612
American Medical Association (AMA)
Wolthers, Ole D.. Component-Resolved Diagnosis in Pediatrics. ISRN Pediatrics. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-499612
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499612