Grade 1 Endometrioid Endometrial Carcinoma Presenting with Pelvic Bone Metastasis : A Case Report and Review of the Literature

Abstract EN

Most grade 1 endometrioid endometrial cancers are confined to the uterus at the time of diagnosis and confer a good prognosis.

Rarely will a grade 1 endometrioid endometrial carcinoma present with distant metastasis, especially to the bone.

We present the case of a 56-year-old woman with postmenopausal bleeding and right hip pain due to metastatic grade 1 endometrioid uterine cancer invading into the right ischium.

We discuss treatment options as well as provide a review of prior published reports on bony metastasis in grade 1 endometrioid endometrial cancers.

To date, this case is one of 10 others which demonstrates that even a well-differentiated, low-grade endometrioid endometrial carcinoma can progress in a highly aggressive manner.