Labor Augmentation with Oxytocin Decreases Glutathione Level
Joint Authors
Silberstein, Tali
Burg, Ariela
Saphier, Oshra
Tavor, Dorith
Schneid-Kofman, Naomi
Shai, Iris
Source
Obstetrics and Gynecology International
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-04-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
To compare oxidative stress following spontaneous vaginal delivery with that induced by Oxytocin augmented delivery.
Methods.
98 women recruited prior to labor.
57 delivered spontaneously, while 41 received Oxytocin for augmentation of labor.
Complicated deliveries and high-risk pregnancies were excluded.
Informed consent was documented.
Arterial cord blood gases, levels of Hematocrit, Hemoglobin, and Bilirubin were studied.
Glutathione (GSH) concentration was measured by a spectroscopic method.
Plasma and red blood cell (RBC) levels of Malondialdehyde indicated lipid peroxidation.
RBC uptake of phenol red denoted cell penetrability.
SPSS data analysis was used.
Results.
Cord blood GSH was significantly lower in the Oxytocin group (2.3±0.55 mM versus 2.55±0.55 mM, P=.01).
No differences were found in plasma or RBC levels of MDA or in uptake of Phenol red between the groups.
Conclusion.
Lower GSH levels following Oxytocin augmentation indicate an oxidative stress, though selected measures of oxidative stress demonstrate no cell damage.
American Psychological Association (APA)
Schneid-Kofman, Naomi& Silberstein, Tali& Saphier, Oshra& Shai, Iris& Tavor, Dorith& Burg, Ariela. 2009. Labor Augmentation with Oxytocin Decreases Glutathione Level. Obstetrics and Gynecology International،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-499682
Modern Language Association (MLA)
Schneid-Kofman, Naomi…[et al.]. Labor Augmentation with Oxytocin Decreases Glutathione Level. Obstetrics and Gynecology International No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-499682
American Medical Association (AMA)
Schneid-Kofman, Naomi& Silberstein, Tali& Saphier, Oshra& Shai, Iris& Tavor, Dorith& Burg, Ariela. Labor Augmentation with Oxytocin Decreases Glutathione Level. Obstetrics and Gynecology International. 2009. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-499682
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499682