Efficacy of Crest Herbal Toothpaste in “Clearing Internal Heat” : A Randomized, Double-Blind Clinical Study
Joint Authors
Li, Xiao-Hong
Wang, Shao-Xian
Liu, Yue-Yun
Chen, Jia-Xu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
Evaluation of the efficacy of Crest Herbal Crystal Toothpaste in “clearing internal heat.” Methods.
This was a randomized, double-blind, controlled parallel design clinical test of a product that was already on the market.
72 subjects were randomly assigned to control group (group A with Colgate Herbal Salty Toothpaste) or treatment group (group B with Crest Herbal Crystal Toothpaste) with ratio of 1 : 2.
Subjects were instructed to brush with 1g toothpaste for 2 minutes each time, 2 times per day in a 4-aweek test period; measurement with the rating scale on the efficacy of “clearing internal heat” for the herbal toothpaste was done at baseline, 2 weeks, and 4 weeks of toothpaste usage.
Results.
The rating scale on efficacy of “clearing internal heat” for the herbal toothpaste reveals that the primitive points of 72-case intention-to-treat (ITT) analysis and 67-case per-protocol (PP) analysis for subjects in group A and subjects in group B were found to be reduced progressively with statistical significance (P<0.05).
The overall effective rates for group A and group B were, respectively, 62.50%, 56.25% (ITT) and 62.50%, 60.64% (PP).
The statistical results indicated that the symptoms of fire-heat for both groups of subjects have been improved after application of toothpaste.
Conclusion.
The efficacy of Crest Herbal Crystal Toothpaste in “clearing internal heat” was confirmed by the trial as compared to Colgate Herbal Salty Toothpaste.
And its efficacy was objectively evaluated by the rating scale on efficacy of “clearing internal heat.”
American Psychological Association (APA)
Chen, Jia-Xu& Liu, Yue-Yun& Wang, Shao-Xian& Li, Xiao-Hong. 2013. Efficacy of Crest Herbal Toothpaste in “Clearing Internal Heat” : A Randomized, Double-Blind Clinical Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-499685
Modern Language Association (MLA)
Chen, Jia-Xu…[et al.]. Efficacy of Crest Herbal Toothpaste in “Clearing Internal Heat” : A Randomized, Double-Blind Clinical Study. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-499685
American Medical Association (AMA)
Chen, Jia-Xu& Liu, Yue-Yun& Wang, Shao-Xian& Li, Xiao-Hong. Efficacy of Crest Herbal Toothpaste in “Clearing Internal Heat” : A Randomized, Double-Blind Clinical Study. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-499685
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499685