PU.1 and Haematopoietic Cell Fate : Dosage Matters

Joint Authors

Mak, Ka Sin
Crossley, Merlin
Funnell, Alister P. W.
Pearson, Richard C. M.

Source

International Journal of Cell Biology

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-08-10

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Biology

Abstract EN

The ETS family transcription factor PU.1 is a key regulator of haematopoietic differentiation.

Its expression is dynamically controlled throughout haematopoiesis in order to direct appropriate lineage specification.

Elucidating the biological role of PU.1 has proved challenging.

This paper will discuss how a range of experiments in cell lines and mutant and transgenic mouse models have enhanced our knowledge of the mechanisms by which PU.1 drives lineage-specific differentiation during haematopoiesis.

American Psychological Association (APA)

Mak, Ka Sin& Funnell, Alister P. W.& Pearson, Richard C. M.& Crossley, Merlin. 2011. PU.1 and Haematopoietic Cell Fate : Dosage Matters. International Journal of Cell Biology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-499748

Modern Language Association (MLA)

Mak, Ka Sin…[et al.]. PU.1 and Haematopoietic Cell Fate : Dosage Matters. International Journal of Cell Biology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-499748

American Medical Association (AMA)

Mak, Ka Sin& Funnell, Alister P. W.& Pearson, Richard C. M.& Crossley, Merlin. PU.1 and Haematopoietic Cell Fate : Dosage Matters. International Journal of Cell Biology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-499748

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-499748