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Neoadjuvant Use of Photodynamic Therapy in Basal Cell and Squamous Cell Carcinomas of the Face
Joint Authors
Jeremic, Goran
Doyle, Philip C.
Brandt, Michael G.
Moore, Corey C.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
This preliminary study sought to determine the success of photodynamic therapy (PDT) in reducing lesion size in an effort to assess the potential application of this treatment approach in a neoadjuvant role.
Objectives.
To quantify the effects of PDT on lesion area (mm2) for basal cell and squamous cell carcinomas of the face.
Results.
Eighteen participants (10 BCC lesions and 8 SCC lesions of the face) were assessed.
Four lesions (all from the BCC group) showed a complete response to PDT.
Of the remaining 14 lesions, 85.7% (n=12) showed reductions in lesion area, while two lesions showed increase in lesion area.
Proportional reductions for the 12 lesions that did not demonstrate complete response or an increase in area following-PDT were found to range from 13.2% to 85.1% (BCC) and 6.7% to 89.7% (SCC).
Conclusions.
PDT as a neoadjuvant treatment may provide a simple, efficient, and viable approach to reducing the area of malignant lesions of the face with the advantage of reduced cosmetic and aesthetic morbidities.
American Psychological Association (APA)
Jeremic, Goran& Moore, Corey C.& Brandt, Michael G.& Doyle, Philip C.. 2011. Neoadjuvant Use of Photodynamic Therapy in Basal Cell and Squamous Cell Carcinomas of the Face. ISRN Dermatology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-499822
Modern Language Association (MLA)
Jeremic, Goran…[et al.]. Neoadjuvant Use of Photodynamic Therapy in Basal Cell and Squamous Cell Carcinomas of the Face. ISRN Dermatology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-499822
American Medical Association (AMA)
Jeremic, Goran& Moore, Corey C.& Brandt, Michael G.& Doyle, Philip C.. Neoadjuvant Use of Photodynamic Therapy in Basal Cell and Squamous Cell Carcinomas of the Face. ISRN Dermatology. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-499822
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499822