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Preemptive Treatment of Nausea and Vomiting of Pregnancy : Results of a Randomized Controlled Trial
Joint Authors
Koren, Gideon
Maltepe, Caroline
Source
Obstetrics and Gynecology International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objectives.
To determine whether the initiation of treatment (preemptive treatment) before the symptoms of nausea and vomiting of pregnancy (NVP) versus when the symptoms begin can improve the outcome in patients at a high risk for recurrence of severe NVP.
Study Design.
Prospective, randomized controlled trial.
Results.
Preemptive therapy conferred a significant reduction in HG as compared to the previous pregnancy (P=0.047).
In the preemptive arm, there were 2.5-fold fewer cases of moderate-severe cases of NVP than those in the control group (15.4% versus 39.13%) in the first 3 weeks of NVP (P=0.05).
In the preemptive group, significantly more women had their NVP resolved before giving birth (78.2% versus 50%) (P<0.002).
Conclusions.
Preemptive treatment with antiemetics is superior to the treatment that starts only when the symptoms have already occurred in decreasing the risk of severe forms of NVP.
American Psychological Association (APA)
Maltepe, Caroline& Koren, Gideon. 2013. Preemptive Treatment of Nausea and Vomiting of Pregnancy : Results of a Randomized Controlled Trial. Obstetrics and Gynecology International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-499868
Modern Language Association (MLA)
Maltepe, Caroline& Koren, Gideon. Preemptive Treatment of Nausea and Vomiting of Pregnancy : Results of a Randomized Controlled Trial. Obstetrics and Gynecology International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-499868
American Medical Association (AMA)
Maltepe, Caroline& Koren, Gideon. Preemptive Treatment of Nausea and Vomiting of Pregnancy : Results of a Randomized Controlled Trial. Obstetrics and Gynecology International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-499868
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499868