Study on Fracture Healing with Small-Splint-Fixation Therapy by Near-Infrared Raman Spectroscopy
Joint Authors
Chen, Weiwei
Yu, Yun
Chen, Rong
Huang, Hao
Lin, Duo
Feng, Shangyuan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
In this study, near-infrared (NIR) Raman spectroscopy was explored to assess the incorporation of calcium hydroxyapatite (CHA ~960 cm−1) and other biochemical substances during the recovery of rabbits with complete radial fractures treated with or without small splints.
24 rabbits were randomy divided into two groups, one treated with small-splint-fixation therapy and the other without any intervention.
The rabbits were sacrificed at 7, 15, 23, and 30 days after surgery, and the surface layers of the calluses in the fracture healing site from control and treated groups were routinely prepared for Raman spectroscopy.
The prominent Raman bands were observed, including minerals at 430, 590, 960, 1003, and 1071 cm−1, protein at 856, 876, 1246, and 1667 cm−1, and lipid at 1767 cm−1.
The carbonate-to-phosphate ratio (CO3 to υ1 PO4) and the mineral-to-matrix ratio (υ1 PO4 to amide I) were calculated from these normalized Raman bands.
Comparison of the υ1 PO4-to-amide I ratio for the control group with that of the treated group probably indicated that the small-splint-fixation therapy could be useful for the gradual mineralization of the collagen matrix during fracture healing.
American Psychological Association (APA)
Huang, Hao& Feng, Shangyuan& Chen, Weiwei& Yu, Yun& Lin, Duo& Chen, Rong. 2012. Study on Fracture Healing with Small-Splint-Fixation Therapy by Near-Infrared Raman Spectroscopy. Journal of Spectroscopy،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-499892
Modern Language Association (MLA)
Huang, Hao…[et al.]. Study on Fracture Healing with Small-Splint-Fixation Therapy by Near-Infrared Raman Spectroscopy. Journal of Spectroscopy No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-499892
American Medical Association (AMA)
Huang, Hao& Feng, Shangyuan& Chen, Weiwei& Yu, Yun& Lin, Duo& Chen, Rong. Study on Fracture Healing with Small-Splint-Fixation Therapy by Near-Infrared Raman Spectroscopy. Journal of Spectroscopy. 2012. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-499892
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499892