Adjunctive Sitagliptin Therapy in Postoperative Cardiac Surgery Patients : A Pilot Study
Joint Authors
Brackbill, Marcia L.
Sandy, Jeffrey S.
Harralson, Arthur F.
Rahman, Ateequr
Stam, M. Denton
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
We aimed to determine if sitagliptin added to standard postoperative standardized sliding-scale insulin regimens improved blood glucose.
Methods.
A prospective, randomized, double-blind, placebo-controlled pilot study was conducted in diabetic cardiac surgery patients.
Patients received sitagliptin or placebo after surgery for 4 days.
The primary endpoint was to estimate the effect of adjunctive sitagliptin versus placebo on overall mean blood glucose in the 4-day period after surgery.
Results.
Sixty-two patients participated.
Repeated measures tests indicated no significant difference between the groups in the overall mean blood glucose level with a mean of 147.2±4.8 mg/dL and 153.0±4.6 mg/dL for the test and the control group, respectively (P=0.388).
Conclusions.
Sitagliptin added to normal postoperative glucose management practices did not improve overall mean blood glucose control in diabetic patients in the postoperative setting.
American Psychological Association (APA)
Brackbill, Marcia L.& Rahman, Ateequr& Sandy, Jeffrey S.& Stam, M. Denton& Harralson, Arthur F.. 2012. Adjunctive Sitagliptin Therapy in Postoperative Cardiac Surgery Patients : A Pilot Study. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-499962
Modern Language Association (MLA)
Brackbill, Marcia L.…[et al.]. Adjunctive Sitagliptin Therapy in Postoperative Cardiac Surgery Patients : A Pilot Study. International Journal of Endocrinology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-499962
American Medical Association (AMA)
Brackbill, Marcia L.& Rahman, Ateequr& Sandy, Jeffrey S.& Stam, M. Denton& Harralson, Arthur F.. Adjunctive Sitagliptin Therapy in Postoperative Cardiac Surgery Patients : A Pilot Study. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-499962
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-499962