Analytical Expressions for Steady-State Concentrations of Substrate and Oxidized and Reduced Mediator in an Amperometric Biosensor
Joint Authors
Shunmugham, Loghambal
Lakshmanan, Rajendran
Source
International Journal of Electrochemistry
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-24
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
A mathematical model of modified enzyme-membrane electrode for steady-state condition is discussed.
This model contains a nonlinear term related to enzyme kinetics reaction mechanism.
The thickness dependence of an amperometric biosensor is presented both analytically and numerically where the biological layer is immobilized between a solid substrate and permeable electrode.
The analytical expressions pertaining to the concentration of species and normalized current are obtained using the Adomian decomposition method (ADM).
Simple and approximate polynomial expressions of concentrations of an oxidized mediator, substrate, and reduced mediator are derived for all possible values of parameters ϕO2 (Thiele modulus), BO (normalized surface concentration of oxidized mediator), and BS (normalized surface concentration of substrate).
A comparison of the analytical approximation and numerical simulation is also presented.
A good agreement between theoretical predictions and numerical results is observed.
American Psychological Association (APA)
Shunmugham, Loghambal& Lakshmanan, Rajendran. 2013. Analytical Expressions for Steady-State Concentrations of Substrate and Oxidized and Reduced Mediator in an Amperometric Biosensor. International Journal of Electrochemistry،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-500062
Modern Language Association (MLA)
Shunmugham, Loghambal& Lakshmanan, Rajendran. Analytical Expressions for Steady-State Concentrations of Substrate and Oxidized and Reduced Mediator in an Amperometric Biosensor. International Journal of Electrochemistry No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-500062
American Medical Association (AMA)
Shunmugham, Loghambal& Lakshmanan, Rajendran. Analytical Expressions for Steady-State Concentrations of Substrate and Oxidized and Reduced Mediator in an Amperometric Biosensor. International Journal of Electrochemistry. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-500062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500062