Chemokines and Cytokines as Salivary Biomarkers for the Early Diagnosis of Oral Cancer

Joint Authors

Prasad, Gareema
McCullough, Michael J.

Source

International Journal of Dentistry

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-11-26

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Dental

Abstract EN

Chemokines have been shown to be important in both inflammation and carcinogenesis and are able to be measured in saliva with relatively robust methods including enzyme-linked immunosorbent assays (ELISA).

Thus it has been hypothesized that patients with oral cancer and oral potentially malignant lesions will have elevated levels of specific chemokines in oral fluids and that this may be used as a marker of both the early detection of malignant disease and progression to malignancy.

The concept that salivary biomarkers can be easily measured and indicate disease states has profound consequences for clinical practice and may open up new strategies for the diagnosis, prognosis, and potential therapy of oral squamous cell carcinoma (OSCC).

This review focuses on our understanding of cytokines and chemokines and the potential role that they may have in clinical practice.

American Psychological Association (APA)

Prasad, Gareema& McCullough, Michael J.. 2013. Chemokines and Cytokines as Salivary Biomarkers for the Early Diagnosis of Oral Cancer. International Journal of Dentistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-500140

Modern Language Association (MLA)

Prasad, Gareema& McCullough, Michael J.. Chemokines and Cytokines as Salivary Biomarkers for the Early Diagnosis of Oral Cancer. International Journal of Dentistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-500140

American Medical Association (AMA)

Prasad, Gareema& McCullough, Michael J.. Chemokines and Cytokines as Salivary Biomarkers for the Early Diagnosis of Oral Cancer. International Journal of Dentistry. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-500140

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-500140