Shift Work, Jet Lag, and Female Reproduction
Author
Source
International Journal of Endocrinology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Circadian rhythms and “clock gene” expression are involved in successful reproductive cycles, mating, and pregnancy.
Alterations or disruptions of biological rhythms, as commonly occurs in shift work, jet lag, sleep deprivation, or clock gene knock out models, are linked to significant disruptions in reproductive function.
These impairments include altered hormonal secretion patterns, reduced conception rates, increased miscarriage rates and an increased risk of breast cancer.
Female health may be particularly susceptible to the impact of desynchronizing work schedules as perturbed hormonal rhythms can further influence the expression patterns of clock genes.
Estrogen modifies clock gene expression in the uterus, ovaries, and suprachiasmatic nucleus, the site of the primary circadian clock mechanism.
Further work investigating clock genes, light exposure, ovarian hormones, and reproductive function will be critical for indentifying how these factors interact to impact health and susceptibility to disease.
American Psychological Association (APA)
Mahoney, Megan M.. 2010. Shift Work, Jet Lag, and Female Reproduction. International Journal of Endocrinology،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-500141
Modern Language Association (MLA)
Mahoney, Megan M.. Shift Work, Jet Lag, and Female Reproduction. International Journal of Endocrinology No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-500141
American Medical Association (AMA)
Mahoney, Megan M.. Shift Work, Jet Lag, and Female Reproduction. International Journal of Endocrinology. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-500141
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500141