Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs
Joint Authors
Hu, Xiaohong
Zhang, Guojun
Yang, Xiaoli
Hao, Lingyun
Zhang, Xiao
Wang, Guoyu
Wang, Huaiqing
Source
International Journal of Polymer Science
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery.
Hydrogels are the leading materials of soft contact lenses because of their biocompatibility and transparent characteristic.
In order to increase the amount of load drug and to control their release at the expected intervals, many strategies are developed to modify the conventional contact lens as well as the novel hydrogel contact lenses that include (i) polymeric hydrogels with controlled hydrophilic/hydrophobic copolymer ratio; (ii) hydrogels for inclusion of drugs in a colloidal structure dispersed in the contact lenses; (iii) ligand-containing hydrogels; (iv) molecularly imprinted polymeric hydrogels; (v) hydrogel with the surface containing multilayer structure for drugs loading and releasing.
The advantages and disadvantages of these strategies in modifying or designing hydrogel contact lenses for extended ophthalmic drug delivery are analyzed in this paper.
American Psychological Association (APA)
Hu, Xiaohong& Hao, Lingyun& Wang, Huaiqing& Yang, Xiaoli& Zhang, Guojun& Wang, Guoyu…[et al.]. 2011. Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs. International Journal of Polymer Science،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-500182
Modern Language Association (MLA)
Hu, Xiaohong…[et al.]. Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs. International Journal of Polymer Science No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-500182
American Medical Association (AMA)
Hu, Xiaohong& Hao, Lingyun& Wang, Huaiqing& Yang, Xiaoli& Zhang, Guojun& Wang, Guoyu…[et al.]. Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs. International Journal of Polymer Science. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-500182
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500182