Heart of Lymphoma : Primary Mediastinal Large B-Cell Lymphoma with Endomyocardial Involvement
Joint Authors
Bookman, Michael
Jokerst, Clint
Krishnadasan, Ravitharan
Babiker, Hani M.
Miller, Thomas P.
Rogowitz, Elisa
Source
Case Reports in Oncological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Primary mediastinal B-cell lymphoma (PMBCL) is an uncommon aggressive subset of diffuse large B-cell lymphomas.
Although PMBCL frequently spreads locally from the thymus into the pleura or pericardium, it rarely invades directly through the heart.
Herein, we report a case of a young Mexican female diagnosed with PMBCL with clear infiltration of lymphoma through the cardiac wall and into the right atrium and tricuspid valve leading to tricuspid regurgitation.
This was demonstrated by cardiac MRI and transthoracic echocardiogram.
In addition, cardiac MRI and CT scan of the chest revealed the large mediastinal mass completely surrounding and eroding into the superior vena cava (SVC) wall causing a collar of stokes.
The cardiac and SVC infiltration created a significant therapeutic challenge as lymphomas are very responsive to chemotherapy, and treatment could potentially lead to vascular wall rupture and hemorrhage.
Despite the lack of conclusive data on chemotherapy-induced hemodynamic compromise in such scenarios, her progressive severe SVC syndrome and respiratory distress necessitated urgent intervention.
In addition to the unique presentation of this rare lymphoma, our case report highlights the safety of R-CHOP treatment.
American Psychological Association (APA)
Rogowitz, Elisa& Babiker, Hani M.& Krishnadasan, Ravitharan& Jokerst, Clint& Miller, Thomas P.& Bookman, Michael. 2013. Heart of Lymphoma : Primary Mediastinal Large B-Cell Lymphoma with Endomyocardial Involvement. Case Reports in Oncological Medicine،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-500197
Modern Language Association (MLA)
Rogowitz, Elisa…[et al.]. Heart of Lymphoma : Primary Mediastinal Large B-Cell Lymphoma with Endomyocardial Involvement. Case Reports in Oncological Medicine No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-500197
American Medical Association (AMA)
Rogowitz, Elisa& Babiker, Hani M.& Krishnadasan, Ravitharan& Jokerst, Clint& Miller, Thomas P.& Bookman, Michael. Heart of Lymphoma : Primary Mediastinal Large B-Cell Lymphoma with Endomyocardial Involvement. Case Reports in Oncological Medicine. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-500197
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500197