A Case of Monoclonal Lymphoplasmacytosis of the Bone Marrow with IgM-Positive Russell Bodies
Joint Authors
Sasaki, Atsushi
Bessho, Masami
Nakamura, Yuichi
Yamaguchi, Hiroshi
Kayano, Hidekazu
Shimada, Tsuneyuki
Wakimoto, Naoki
Shimizu, Michio
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-07
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 71-year-old Japanese male patient infected with HCV was diagnosed with thrombocytopenia.
Histological examination of the bone marrow aspirate showed numerous lymphoid aggregates with Russell bodies.
Immunohistochemistry and flow cytometric analysis demonstrated clonal expansion of CD5+ CD23+ B cells.
Russell bodies were positive for IgM and lambda immunoglobulin light chain.
The patient also underwent gastric biopsy, which revealed Helicobacter pylori (HP) infection.
Subsequent eradication of the bacteria resulted in improvement of his thrombocytopenia.
The clinical course remained uneventful at 15-month follow-up, consistent with monoclonal B-cell lymphocytosis.
The observed clonal expansion with plasmacytic differentiation may have occurred under the influence of HCV with HP infection.
American Psychological Association (APA)
Kayano, Hidekazu& Shimada, Tsuneyuki& Wakimoto, Naoki& Nakamura, Yuichi& Bessho, Masami& Yamaguchi, Hiroshi…[et al.]. 2011. A Case of Monoclonal Lymphoplasmacytosis of the Bone Marrow with IgM-Positive Russell Bodies. Bone Marrow Research،Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-500204
Modern Language Association (MLA)
Kayano, Hidekazu…[et al.]. A Case of Monoclonal Lymphoplasmacytosis of the Bone Marrow with IgM-Positive Russell Bodies. Bone Marrow Research No. 2011 (2011), pp.1-3.
https://search.emarefa.net/detail/BIM-500204
American Medical Association (AMA)
Kayano, Hidekazu& Shimada, Tsuneyuki& Wakimoto, Naoki& Nakamura, Yuichi& Bessho, Masami& Yamaguchi, Hiroshi…[et al.]. A Case of Monoclonal Lymphoplasmacytosis of the Bone Marrow with IgM-Positive Russell Bodies. Bone Marrow Research. 2011. Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-500204
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500204