The Role of Lymphadenectomy in Surgical Staging of Endometrial Cancer
Joint Authors
Lurain, John R.
Neubauer, Nikki L.
Source
International Journal of Surgical Oncology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Surgical staging, including lymph node sampling, for endometrial cancer was adopted by the International Federation of Gynecology and Obstetrics (FIGO) in 1988 based on reports demonstrating diagnostic and therapeutic advantages.
This review focuses on the incidence of lymph node metastasis, risk factors for lymph node involvement, the effect of lymph node metastasis on prognosis, the therapeutic effect and diagnostic usefulness of lymphadenectomy, risks of lymph node dissection, and future directions in surgical staging of endometrial cancer.
Surgical staging identifies most patients with extrauterine disease as well as uterine risk factors for recurrence, thereby allowing for a more informed approach to postoperative adjuvant therapy.
Lymphadenectomy as a part of surgical staging is not required in patients assessed intraoperatively to be at low risk for lymph node metastasis (<2 cm grade 1 tumors with superficial myometrial invasion), however, a systematic lymph node dissection should be performed in most other patients with endometrial cancer.
In the future, molecular markers may be useful to predict preoperatively tumor aggressiveness and lymph node metastasis.
It is hoped that an approach of surgical staging with selective lymph node dissection will improve survival and spare patients additional surgical complications or unnecessary postoperative exposure to radiation and/or chemotherapy.
American Psychological Association (APA)
Neubauer, Nikki L.& Lurain, John R.. 2011. The Role of Lymphadenectomy in Surgical Staging of Endometrial Cancer. International Journal of Surgical Oncology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-500220
Modern Language Association (MLA)
Neubauer, Nikki L.& Lurain, John R.. The Role of Lymphadenectomy in Surgical Staging of Endometrial Cancer. International Journal of Surgical Oncology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-500220
American Medical Association (AMA)
Neubauer, Nikki L.& Lurain, John R.. The Role of Lymphadenectomy in Surgical Staging of Endometrial Cancer. International Journal of Surgical Oncology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-500220
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500220