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Association between Helicobacter pylori Infection and Risk of Osteoporosis in Elderly Taiwanese Women with Upper Gastrointestinal Diseases : A Retrospective Patient Record Review
Joint Authors
Lin, Shih-Chun
Koo, Malcolm
Tsai, Kun-Wei
Source
Gastroenterology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Helicobacter pylori (H.
pylori) infection could lead to chronic local and systemic immune response.
The resulting increase in proinflammatory cytokines could affect bone resorption and might increase the risk of osteoporosis.
This study aimed to investigate the association between H.
pylori infection and osteoporosis in elderly female patients with upper gastrointestinal diseases.
Methods.
A retrospective patient record review study was conducted in a regional teaching hospital in south Taiwan.
Relevant information on female patients aged 65 and over who were diagnosed with diseases of esophagus, gastric ulcer, or duodenal ulcer during January 2008 to December 2010 were abstracted.
Association between H.
pylori infection and osteoporosis was evaluated using multivariate logistic regression analysis.
Results.
Of the 365 patients with a mean age of 77.3 years, 77 (21.1%) had H.
pylori infection and 101 (27.7%) had been diagnosed with osteoporosis.
Multivariate logistic regression analysis revealed that osteoporosis was significantly associated with H.
pylori infection (adjusted odds ratio = 2.03, 95% confidence interval = 1.14–3.62) after adjusting for age group, body mass index group, and use of proton pump inhibitor.
Conclusion.
Osteoporosis was found to be associated with H.
pylori infection in Taiwanese female patients with upper gastrointestinal diseases.
Further studies with information on potential confounders are needed to confirm the association.
American Psychological Association (APA)
Lin, Shih-Chun& Koo, Malcolm& Tsai, Kun-Wei. 2014. Association between Helicobacter pylori Infection and Risk of Osteoporosis in Elderly Taiwanese Women with Upper Gastrointestinal Diseases : A Retrospective Patient Record Review. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-500233
Modern Language Association (MLA)
Lin, Shih-Chun…[et al.]. Association between Helicobacter pylori Infection and Risk of Osteoporosis in Elderly Taiwanese Women with Upper Gastrointestinal Diseases : A Retrospective Patient Record Review. Gastroenterology Research and Practice No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-500233
American Medical Association (AMA)
Lin, Shih-Chun& Koo, Malcolm& Tsai, Kun-Wei. Association between Helicobacter pylori Infection and Risk of Osteoporosis in Elderly Taiwanese Women with Upper Gastrointestinal Diseases : A Retrospective Patient Record Review. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-500233
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500233