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Developmental Neurotoxicity : Some Old and New Issues
Joint Authors
Costa, Lucio Guido
Giordano, Gennaro
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-24
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The developing central nervous system is often more vulnerable to injury than the adult one.
Of the almost 200 chemicals known to be neurotoxic, many are developmental neurotoxicants.
Exposure to these compounds in utero or during childhood can contribute to a variety of neurodevelopmental and neurological disorders.
Two established developmental neurotoxicants, methylmercury and lead, and two classes of chemicals, the polybrominated diphenyl ether flame retardants and the organophosphorus insecticides, which are emerging as potential developmental neurotoxicants, are discussed in this paper.
Developmental neurotoxicants may also cause silent damage, which would manifest itself only as the individual ages, and may contribute to neurodegenerative diseases such as Parkinson’s or Alzheimer’s diseases.
Guidelines for developmental neurotoxicity testing have been implemented, but there is still room for their improvement and for searching and validating alternative testing approaches.
American Psychological Association (APA)
Giordano, Gennaro& Costa, Lucio Guido. 2012. Developmental Neurotoxicity : Some Old and New Issues. ISRN Toxicology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-500239
Modern Language Association (MLA)
Giordano, Gennaro& Costa, Lucio Guido. Developmental Neurotoxicity : Some Old and New Issues. ISRN Toxicology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-500239
American Medical Association (AMA)
Giordano, Gennaro& Costa, Lucio Guido. Developmental Neurotoxicity : Some Old and New Issues. ISRN Toxicology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-500239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500239