Predictors of Treatment with Duloxetine or Venlafaxine XR among Adult Patients Treated for Depression in Primary Care Practices in the United Kingdom
Joint Authors
Durden, Emily
Torres, Amelito
Shi, Nianwen
Cao, Zhun
Happich, Michael
Source
Depression Research and Treatment
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Knowledge about real-world use of duloxetine and venlafaxine XR to treat depression in the UK is limited.
Aims.
To identify predictors of duloxetine or venlafaxine XR initiation.
Method.
Adult depressed patients who initiated duloxetine or venlafaxine XR between January 1, 2006 and September 30, 2007 were identified in the UK’s General Practice Research Database.
Demographic and clinical predictors of treatment initiation with duloxetine and venlafaxine XR were identified using logistic regression.
Results.
Patients initiating duloxetine (n=909) were 4 years older than venlafaxine XR recipients (n=1286).
Older age, preexisting unexplained pain, respiratory disease, and pre-period use of anticonvulsants, opioids, and antihyperlipidemics were associated with increased odds of initiating duloxetine compared to venlafaxine XR.
Pre-period anxiety disorder was associated with decreased odds of receiving duloxetine.
Conclusion.
Initial treatment choice with duloxetine versus venlafaxine XR was primarily driven by patient-specific mental and medical health characteristics.
General practitioners in the UK favor duloxetine over venlafaxine XR when pain conditions coexist with depression.
American Psychological Association (APA)
Shi, Nianwen& Durden, Emily& Torres, Amelito& Cao, Zhun& Happich, Michael. 2012. Predictors of Treatment with Duloxetine or Venlafaxine XR among Adult Patients Treated for Depression in Primary Care Practices in the United Kingdom. Depression Research and Treatment،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-500305
Modern Language Association (MLA)
Shi, Nianwen…[et al.]. Predictors of Treatment with Duloxetine or Venlafaxine XR among Adult Patients Treated for Depression in Primary Care Practices in the United Kingdom. Depression Research and Treatment No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-500305
American Medical Association (AMA)
Shi, Nianwen& Durden, Emily& Torres, Amelito& Cao, Zhun& Happich, Michael. Predictors of Treatment with Duloxetine or Venlafaxine XR among Adult Patients Treated for Depression in Primary Care Practices in the United Kingdom. Depression Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-500305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500305