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Cubic and Hexagonal Liquid Crystals as Drug Delivery Systems
Joint Authors
Gui, Shuangying
Chen, Yulin
Ma, Ping
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-05
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Lipids have been widely used as main constituents in various drug delivery systems, such as liposomes, solid lipid nanoparticles, nanostructured lipid carriers, and lipid-based lyotropic liquid crystals.
Among them, lipid-based lyotropic liquid crystals have highly ordered, thermodynamically stable internal nanostructure, thereby offering the potential as a sustained drug release matrix.
The intricate nanostructures of the cubic phase and hexagonal phase have been shown to provide diffusion controlled release of active pharmaceutical ingredients with a wide range of molecular weights and polarities.
In addition, the biodegradable and biocompatible nature of lipids demonstrates the minimum toxicity and thus they are used for various routes of administration.
Therefore, the research on lipid-based lyotropic liquid crystalline phases has attracted a lot of attention in recent years.
This review will provide an overview of the lipids used to prepare cubic phase and hexagonal phase at physiological temperature, as well as the influencing factors on the phase transition of liquid crystals.
In particular, the most current research progresses on cubic and hexagonal phases as drug delivery systems will be discussed.
American Psychological Association (APA)
Chen, Yulin& Ma, Ping& Gui, Shuangying. 2014. Cubic and Hexagonal Liquid Crystals as Drug Delivery Systems. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-500360
Modern Language Association (MLA)
Chen, Yulin…[et al.]. Cubic and Hexagonal Liquid Crystals as Drug Delivery Systems. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-500360
American Medical Association (AMA)
Chen, Yulin& Ma, Ping& Gui, Shuangying. Cubic and Hexagonal Liquid Crystals as Drug Delivery Systems. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-500360
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500360