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Wound Healing Activity of Rubus sanctus Schreber (Rosaceae) : Preclinical Study in Animal Models
Joint Authors
Akkol, Esra Küpeli
Keleş, Hikmet
Süntar, Ipek
Koca, Ufuk
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Young shoots of Rubus species have been used for healing of wounds, infected insect bites and pimples in folk medicine for ages.
In order to evaluate the wound healing activity of Rubus sanctus, four different extracts were prepared from the whole aerial parts of the plant by using n-hexane, chloroform, ethyl acetate and methanol, respectively.
Incision wound healing model by using tensiometer on rats and excision model on mice were employed to assess the activity.
Remarkable wound healing activity was observed with the ointment formulation of the methanol extract at 1% concentration on the mentioned models.
The results of histopathological examination also supported the outcome of both incision and excision wound models.
The wound healing effect was comparatively evaluated with a reference ointment Madecassol.
The experimental data confirmed the ethnobotanical usage of R.
sanctus.
American Psychological Association (APA)
Süntar, Ipek& Koca, Ufuk& Keleş, Hikmet& Akkol, Esra Küpeli. 2011. Wound Healing Activity of Rubus sanctus Schreber (Rosaceae) : Preclinical Study in Animal Models. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-500377
Modern Language Association (MLA)
Süntar, Ipek…[et al.]. Wound Healing Activity of Rubus sanctus Schreber (Rosaceae) : Preclinical Study in Animal Models. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-500377
American Medical Association (AMA)
Süntar, Ipek& Koca, Ufuk& Keleş, Hikmet& Akkol, Esra Küpeli. Wound Healing Activity of Rubus sanctus Schreber (Rosaceae) : Preclinical Study in Animal Models. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-500377
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500377