Vascular Endothelial Growth Factor Inhibitor-Induced Hypertension : Basics for Primary Care Providers
Joint Authors
Escalante, Carmen P.
Zalpour, Ali
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Frequently, primary care providers continue to manage the overall medical care of cancer patients.
With newer and often more potent antitumor agents, patients may present to their local physicians with drug-induced toxicities such as hypertension induced by vascular endothelial growth factor (VEGF) inhibitors.
It is imperative that these healthcare providers are aware of basic aspects of this drug class, as its use has increased significantly in the last several years.
Uncontrolled or malignant hypertension due to these agents should be recognized readily and treated early to prevent more severe outcomes.
This overview provides a brief background on the role of VEGF and angiogenesis in tumor metabolism as well as theories of the mechanism of VEGF inhibitors and hypertension.
Helpful clinical practice aspects including the types of inhibitors used in the United States and their pharmacologic characteristics will be discussed.
Also, diagnosis and treatment of hypertension induced by vascular endothelial growth factors are reviewed.
A summary of key aspects of this drug class and hypertension is included.
American Psychological Association (APA)
Escalante, Carmen P.& Zalpour, Ali. 2011. Vascular Endothelial Growth Factor Inhibitor-Induced Hypertension : Basics for Primary Care Providers. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-500439
Modern Language Association (MLA)
Escalante, Carmen P.& Zalpour, Ali. Vascular Endothelial Growth Factor Inhibitor-Induced Hypertension : Basics for Primary Care Providers. Cardiology Research and Practice No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-500439
American Medical Association (AMA)
Escalante, Carmen P.& Zalpour, Ali. Vascular Endothelial Growth Factor Inhibitor-Induced Hypertension : Basics for Primary Care Providers. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-500439
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500439