Fertility-Preserving Surgery in Patients with Early Stage Cervical Carcinoma
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-18
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Fertility preservation is an important issue for patients in reproductive age with early stage cervical cancer.
In view of recent developments, our purpose was to review and discuss available surgical alternatives.
A literature search was conducted using PUBMED, including papers between 1980 and December 2011.
In patients with stage IA1 cervical cancer, conization is a valid alternative.
Patients with stage IA2-IB1 disease can be conservatively treated by radical trachelectomy.
This is as well-established conservative approach and appears to be safe and effective in allowing a high chance of conception.
Prematurity is the most serious issue in pregnancies following trachelectomy.
Less invasive options such as simple trachelectomy or conization seem to be feasible for stages IA2-IB1, but more and better evidence is needed.
Neoadjuvant therapy might allow conservative surgery to be performed also in patients with more extensive lesions.
Ovarian transposition is important when adjuvant radiation is needed.
In conclusion, available literature shows that there are interesting fertility-sparing treatment alternatives to the “golden standard” for the management of early cervical cancer in young women.
American Psychological Association (APA)
Kardakis, Spyridon. 2012. Fertility-Preserving Surgery in Patients with Early Stage Cervical Carcinoma. ISRN Oncology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-500461
Modern Language Association (MLA)
Kardakis, Spyridon. Fertility-Preserving Surgery in Patients with Early Stage Cervical Carcinoma. ISRN Oncology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-500461
American Medical Association (AMA)
Kardakis, Spyridon. Fertility-Preserving Surgery in Patients with Early Stage Cervical Carcinoma. ISRN Oncology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-500461
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500461