Using Aptamers for Cancer Biomarker Discovery
Joint Authors
Donovan, Michael J.
Chang, Yun Min
Tan, Weihong
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aptamers are single-stranded synthetic DNA- or RNA-based oligonucleotides that fold into various shapes to bind to a specific target, which includes proteins, metals, and molecules.
Aptamers have high affinity and high specificity that are comparable to that of antibodies.
They are obtained using iterative method, called (Systematic Evolution of Ligands by Exponential Enrichment) SELEX and cell-based SELEX (cell-SELEX).
Aptamers can be paired with recent advances in nanotechnology, microarray, microfluidics, and other technologies for applications in clinical medicine.
One particular area that aptamers can shed a light on is biomarker discovery.
Biomarkers are important in diagnosis and treatment of cancer.
In this paper, we will describe ways in which aptamers can be used to discover biomarkers for cancer diagnosis and therapeutics.
American Psychological Association (APA)
Chang, Yun Min& Donovan, Michael J.& Tan, Weihong. 2013. Using Aptamers for Cancer Biomarker Discovery. Journal of Nucleic Acids،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-500494
Modern Language Association (MLA)
Chang, Yun Min…[et al.]. Using Aptamers for Cancer Biomarker Discovery. Journal of Nucleic Acids No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-500494
American Medical Association (AMA)
Chang, Yun Min& Donovan, Michael J.& Tan, Weihong. Using Aptamers for Cancer Biomarker Discovery. Journal of Nucleic Acids. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-500494
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500494
