Comparison of Staging Systems of Hepatocellular Carcinoma
Joint Authors
Tovikkai, Chutwichai
Sirivatanauksorn, Yongyut
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Many staging systems of hepatocellular carcinoma (HCC) were established; however, there is no consensus on which is proper in predicting prognosis.
This study aims to evaluate various commonly used staging systems of HCC.
Patients who underwent surgery during 2001–2007 were included.
All patient data were retrospectively staged using six staging systems, that are American Joint Committee on Cancer (AJCC) Tumour-Node-Metastasis (TNM), Okuda staging, Cancer of the Liver Italian Program (CLIP), Barcelona Clinic Liver Cancer (BCLC), Chinese University Prognostic Index (CUPI), and Japan Integrated Staging (JIS).
Child-Pugh classification was also evaluated.
The staging systems were compared by mean of overall and disease-free survival.
Total of 99 patient data were enrolled in the analyses.
All staging systems except Okuda were significant in determining overall survival in univariate analyses.
In multivariate analyses, TNM and Child-Pugh demonstrated better predictive power for overall survival.
In terms of disease-free survival, univariate analyses revealed that TNM, CLIP, BCLC, CUPI, and JIS were significant, and TNM was the best predictive staging system in multivariate analyses.
In our study, TNM and Child-Pugh are the representative systems in predicting survival of HCC patients who undergo surgical resection.
Moreover, they are practical and easily assessable in clinical practice.
American Psychological Association (APA)
Sirivatanauksorn, Yongyut& Tovikkai, Chutwichai. 2011. Comparison of Staging Systems of Hepatocellular Carcinoma. HPB Surgery،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-500557
Modern Language Association (MLA)
Sirivatanauksorn, Yongyut& Tovikkai, Chutwichai. Comparison of Staging Systems of Hepatocellular Carcinoma. HPB Surgery No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-500557
American Medical Association (AMA)
Sirivatanauksorn, Yongyut& Tovikkai, Chutwichai. Comparison of Staging Systems of Hepatocellular Carcinoma. HPB Surgery. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-500557
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500557