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Prolonged Antigen Ingestion by Sensitized Mice Ameliorates Airway Inflammation
Joint Authors
Cara, Denise Carmona
Noviello, Maria de Lourdes Meirelles
Dourado, Luana Pereira Antunes
Batista, Nathália Vieira
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Food allergy frequently precedes or coexists with respiratory allergy, and although restriction of contacts with the allergen is the elected clinical procedure, oral immunotherapy (OIT) has proven to be surprisingly efficient in clinical trials.
We investigated whether prolonged restriction and voluntary exposure of previously sensitized (immunized) mice to ovalbumin (OVA) in the drinking water would alter subsequent responses to bronchial (aerosol) challenge with OVA.
We found a significant suppression of bronchial inflammation, with marked reduction of eosinophils.
IL-4, CCL-2, and CCL-11 are not associated with elevation in IL-10 production or Foxp3 expression, with only minor digestive symptoms.
American Psychological Association (APA)
Noviello, Maria de Lourdes Meirelles& Batista, Nathália Vieira& Dourado, Luana Pereira Antunes& Cara, Denise Carmona. 2011. Prolonged Antigen Ingestion by Sensitized Mice Ameliorates Airway Inflammation. ISRN Allergy،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-500559
Modern Language Association (MLA)
Noviello, Maria de Lourdes Meirelles…[et al.]. Prolonged Antigen Ingestion by Sensitized Mice Ameliorates Airway Inflammation. ISRN Allergy No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-500559
American Medical Association (AMA)
Noviello, Maria de Lourdes Meirelles& Batista, Nathália Vieira& Dourado, Luana Pereira Antunes& Cara, Denise Carmona. Prolonged Antigen Ingestion by Sensitized Mice Ameliorates Airway Inflammation. ISRN Allergy. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-500559
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500559