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A Novel Kinetic Spectrophotometric Method for the Determination of Dopamine in Biological and Pharmaceutical Samples
Joint Authors
Nasirizadeh, N.
Asgharpoor, Adel
Shishehbore, Masoud Reza
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A sensitive and accurate method for quantitative determination of dopamine was introduced.
The proposed method is based on inhibitory effect of dopamine on the oxidation of thionine by bromate in acidic media.
The change in absorbance was followed spectrophotometrically at 601 nm.
The dependence of sensitivity on the reaction variables was investigated and optimized to obtain the maximum sensitivity.
Under optimum experimental conditions, calibration curve was linear over the range 0.2–103.3 μg mL−1 of dopamine.
The relative standard deviations (n=6) of 0.5, 1.0, 5.0, and 30.0 μg mL−1 of dopamine were 1.13, 1.02, 0.99, and 0.97%, respectively.
The limit of detection was 0.057 μg mL−1 of dopamine.
The effect of diverse species was also investigated.
The developed method was successfully applied for the determination of dopamine in pharmaceutical and biological samples.
American Psychological Association (APA)
Shishehbore, Masoud Reza& Asgharpoor, Adel& Nasirizadeh, N.. 2013. A Novel Kinetic Spectrophotometric Method for the Determination of Dopamine in Biological and Pharmaceutical Samples. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-500666
Modern Language Association (MLA)
Shishehbore, Masoud Reza…[et al.]. A Novel Kinetic Spectrophotometric Method for the Determination of Dopamine in Biological and Pharmaceutical Samples. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-500666
American Medical Association (AMA)
Shishehbore, Masoud Reza& Asgharpoor, Adel& Nasirizadeh, N.. A Novel Kinetic Spectrophotometric Method for the Determination of Dopamine in Biological and Pharmaceutical Samples. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-500666
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500666