DSC Study of Collagen in Disc Disease
Joint Authors
Skrzyński, S.
Marciniak, A.
Sionkowska, A.
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Differential scanning calorimetry (DSC) has been used to estimate the effect of disc disease on the collagen helix-coil transition and morphology for tissue extracted from patients during surgical operation.
Forty discs were obtained from patients with degenerative disc disease undergoing surgery for low back pain.
The patients were in the age between 20 and 70 years old.
The specimens were kept wet during DSC experiment.
The data allow the comparison between thermal stability of collagen tissue from healthy patients and from patients suffering from disc disease.
In the paper the comparison between thermal helix-coil transition for collagen fibers from patients suffering from disc disease and collagen fibers from healthy organisms has been discussed.
The heating rate has an influence on the position on denaturation temperatures of collagen in disc tissues.
Higher helix-coil transition temperature of collagen in degenerated disc suggests that additional intermolecular cross linking of collagen fibers occurs.
Denaturation temperatures of collagen in degenerated male disc possess smaller values than in female ones.
Disc disease induces changes in collagen structure and leads to formation of additional crosslinks between collagen fibers.
American Psychological Association (APA)
Skrzyński, S.& Sionkowska, A.& Marciniak, A.. 2010. DSC Study of Collagen in Disc Disease. Journal of Biophysics،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-500691
Modern Language Association (MLA)
Skrzyński, S.…[et al.]. DSC Study of Collagen in Disc Disease. Journal of Biophysics No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-500691
American Medical Association (AMA)
Skrzyński, S.& Sionkowska, A.& Marciniak, A.. DSC Study of Collagen in Disc Disease. Journal of Biophysics. 2010. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-500691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500691